HEALTHY CONTROLS GROUP - AGE AND SEX-MATCHED

This study looks at how stress and personality traits influence decision-making in people with borderline personality disorder (BPD) compared to healthy adults. About 106 participants aged 18-45 will complete online tasks, a stress test, surveys, and have their heart rate, sweat …

This observational study compares how people with bronchiectasis and healthy volunteers respond to different exercise tests, including a 6-minute stepper test, a 6-minute walk test, and a 1-minute sit-to-stand test. Researchers will measure breathing, heart rate, and muscle stren…

This observational study at Yale University aims to understand how people with opioid use disorder (OUD) learn to avoid pain compared to healthy individuals. About 180 participants will perform a learning task inside an fMRI scanner to measure brain activity. Those with OUD will …

This study investigates how colored light affects pain by scanning the brains of 60 people—half with chronic musculoskeletal pain (like fibromyalgia) and half healthy. Participants will view different light patterns while their brain activity is measured, and some will also recei…

This study aims to understand why some people get stuck in repetitive negative thinking, common in depression and anxiety. Researchers will compare brain activity in 50 patients and 50 healthy volunteers using a harmless brain-imaging device during emotion tasks. The goal is to u…

This study looks at two new tests—a walking adaptability ladder test and a foot tap test—to see if they can detect subtle walking and movement problems in people with mild multiple sclerosis (MS). Researchers will compare results from 100 participants (people with mild MS and hea…

This study checks if a simple online cognitive test (Creyos) can accurately track memory and thinking changes in older adults with mild cognitive impairment or past depression. About 150 participants will take both online and in-person tests over up to 5 years. The goal is to see…