Can tylenol and advil replace opioids after tubal ligation?

NCT ID NCT06434233

Recruiting now Symptom relief Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two pain management plans after laparoscopic tubal sterilization: one with opioids and one without. About 38 women will report their pain levels and satisfaction. The goal is to see if non-opioid drugs like Tylenol and ibuprofen work just as well.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Acetaminophen, Ibuprofen, and Oxycodone
What this could lead to: If successful, this could show that non-opioid painkillers are enough for pain after tubal sterilization, reducing the need for opioid prescriptions.
What could go wrong: This is a small, early-phase trial with only 38 participants, so results may not apply to everyone. Pain is subjective, and some people may still need opioids.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

female infertility opioid abuse Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OPIOID USE POST-OPERATIVE PAIN STERILITY, FEMALE

Contacts and locations

Locations

Johns Hopkins Bayview Medical Center
RECRUITING

Baltimore, Maryland, 21224, United States

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