Can tylenol and advil replace opioids after sterilization surgery?

NCT ID NCT06434233

First seen Nov 12, 2025 · Last updated Jun 23, 2026 · Updated 36 times

Summary

This study compares pain control using only non-opioid drugs (acetaminophen and ibuprofen) versus including an opioid (oxycodone) after laparoscopic tubal sterilization. About 38 women undergoing the procedure will report their pain scores and satisfaction. The goal is to see if avoiding opioids still provides adequate pain relief.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for POST-OPERATIVE PAIN are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins Bayview Medical Center

    RECRUITING

    Baltimore, Maryland, 21224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Acetaminophen, Ibuprofen, and Oxycodone

What this could lead to

If successful, this could show that non-opioid painkillers are enough for pain after tubal sterilization, reducing the need for opioid prescriptions.

What could go wrong

This is a small, early-phase trial with only 38 participants, so results may not apply to everyone. Pain is subjective, and some patients may still need opioids.

Conditions

The condition(s) this trial relates to.

female infertility opioid abuse Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.