New hope for Parkinson's patients: opicapone study targets motor fluctuations

NCT ID NCT07403799

First seen Jun 27, 2026 · Last updated Jul 14, 2026 · Updated 2 times

Summary

This study looks at how well the drug opicapone works for people with Parkinson's disease who have early signs of motor fluctuations (times when movement symptoms change). About 200 adults in Italy will take the drug as part of their normal care. Researchers will check if patients feel better after 12 months using a simple questionnaire.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • A.O.U Città della Salute e della Scienza di Torino

    Turin, 10126, Italy

  • ARNAS Azienda Ospedaliera Brotzu

    Cagliari, 09121, Italy

  • ASST Gaetano Pini CTO, Centro Parkinson

    Milan, 20126, Italy

  • ASST Spedali Civili di Brescia

    Brescia, 25123, Italy

  • Arcispedale S. Maria Nuova (AUSL RE)

    Reggio Emilia, 42123, Italy

  • Azienda Ospedaliera di Perugia (Santa Maria della Misericordia)

    Perugia, 06100, Italy

  • Centro Neurolesi Bonino Pulejo Messina/IRCCS

    Messina, 98123, Italy

  • Fondazione Mondino

    Pavia, 27100, Italy

  • Istituto Neurologico Carlo Besta - Fondazione IRCCS

    Milan, 20133, Italy

  • Ospedale Borgo Roma

    Verona, 37134, Italy

  • Ospedale Mater Domini

    Catanzaro, 88100, Italy

  • Ospedale Policlinico San Martino

    Genova, 16132, Italy

  • Ospedale SS Annunziata

    Chieti, 66100, Italy

  • Ospedale Santa Chiara

    Pisa, 56126, Italy

  • Policlinico Tor Vergata

    Roma, 00133, Italy

  • Policlinico Umberto I

    Roma, 00161, Italy

  • Policlinico Universitario Campus Bio-Medico

    Roma, 00128, Italy

  • Policlinico Universitario Fondazione Agostino Gemelli

    Roma, 00168, Italy

  • Policlinico di Bari Ospedale Giovanni XXIII, Clinica Neurologia AMADUCCI

    Bari, 70124, Italy

  • U.O di Neurologia, Policlinico P. Giaccone

    Palermo, 90129, Italy

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