New drug cocktail shows promise for Tough-to-Treat recurrent cancers

NCT ID NCT02208375

First seen Nov 06, 2025 · Last updated Apr 29, 2026 · Updated 19 times

Summary

This study tests two drug combinations (olaparib plus either vistusertib or capivasertib) in people with endometrial, triple-negative breast, ovarian, or related cancers that returned after prior treatment. The main goal is to find the safest dose and understand side effects. About 159 adults will take part, and the drugs work by blocking enzymes that help cancer cells grow.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.