Precision radiation targets hidden prostate cancer spots

NCT ID NCT06392295

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving radiation to the para-aortic lymph nodes (located in the abdomen) can better control prostate cancer that has returned in a limited number of spots. Men with hormone-sensitive prostate cancer and up to five lesions seen on a PSMA PET/CT scan will receive daily radiation for five weeks, along with standard hormone therapy. The goal is to improve cancer control and maintain quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radiation therapy (photon or proton) to para-aortic and pelvic lymph nodes

What this could lead to

If successful, this approach could offer a more targeted way to control prostate cancer that has spread to lymph nodes, potentially delaying the need for stronger treatments.

What could go wrong

This is a small, early-phase trial (34 participants) and may not prove effective for everyone. Radiation to the abdomen carries risks such as fatigue, bowel or bladder irritation, and possible long-term side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate adenocarcinoma prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Miami

    RECRUITING

    Miami, Florida, 33136, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact