New heart device for babies: safer alternative to surgery?

NCT ID NCT05264753

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 255 patients of any age (weighing over 3 kg) who receive a device called the Occlutech PDA Occluder to close a common heart defect called patent ductus arteriosus (PDA). The device is inserted through a blood vessel, avoiding open-heart surgery. Researchers will check safety and effectiveness for up to 3 years after the procedure, looking for serious complications and whether the hole stays closed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Occlutech PDA Occluder (a device inserted through a blood vessel to close a hole in the heart)

What this could lead to

If successful, this could confirm that the device is a safe, non-surgical option to close a common heart defect in children, reducing the need for open-heart surgery.

What could go wrong

This is an observational follow-up study, not a randomized trial, so results may be less definitive. Risks include serious complications like device movement, infection, or stroke, though these are expected to be rare.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

patent ductus arteriosus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aydın Adnan Menderes University Hospital

    RECRUITING

    Aydin, Efeler, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU Sainte-Justine

    NOT_YET_RECRUITING

    Montreal, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Lille - Institut Cœur-Poumon

    NOT_YET_RECRUITING

    Lille, France

    Contact Phone: •••-•••-••••

    Contact

  • Children's Hospital Ireland at Crumlin

    NOT_YET_RECRUITING

    Dublin, Ireland

  • Children´s Hospital, Karolinska University

    NOT_YET_RECRUITING

    Stockholm, Sweden

    Contact

    Contact Email: •••••@•••••

  • Dicle University Hospital

    RECRUITING

    Diyarbakır, SUR, Turkey (Türkiye)

    Contact Email: •••••@•••••

    Contact

    Contact

  • Eskişehir Osmangazi University Hospital

    RECRUITING

    Eskişehir, Eskişehir, 26040, Turkey (Türkiye)

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospital La Rabta

    RECRUITING

    Tunis, Tunisia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Mère Enfant, CHU de Nantes

    RECRUITING

    Nantes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Insel Gruppe

    NOT_YET_RECRUITING

    Bern, Switzerland

    Contact

    Contact

  • Military Hospital

    RECRUITING

    Tunis, Tunisia

    Contact

    Contact Email: •••••@•••••

    Contact

    Contact

  • Ospedale Pediatrico Bambino Gesù

    RECRUITING

    Roma, Roma, 00146, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Rawalpindi Institute of Cardiology

    RECRUITING

    Rawalpindi, Rawalpindi, Pakistan

    Contact

    Contact Email: •••••@•••••

  • Royal Brompton & Harefield Hospitals

    RECRUITING

    London, London, SW3 6NP, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Çukurova University Hospital

    RECRUITING

    Adana, Sarıçam, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact