Liver drug trial for kids with biliary atresia ends early
NCT ID NCT06121375
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested the drug obeticholic acid in children with biliary atresia who had already undergone Kasai surgery. The goal was to see if the drug could improve outcomes like avoiding liver transplant or death. The trial was terminated early and enrolled only 28 participants, so results are limited.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
obeticholic acid
What this could lead to
If it had worked, this could have pointed toward a new treatment to delay or prevent liver transplant in children with biliary atresia.
What could go wrong
The trial was terminated early, so we don't have clear results. It was also a small study, and the drug may not have shown enough benefit or may have caused side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Akdeniz Üniversitesi Tıp Fakültesi Hastanesi Pediatrik Gastroenteroloji
Konyaalti, Antalya, 07050, Turkey (Türkiye)
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Alberta Childrens Hospital
Calgary, Alberta, T3B 6A8, Canada
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Children's Hospital of Fudan University
Shanghai, China
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Children's Hospital of Shanxi
Taiyuan, China
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Children's Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, 310006, China
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Childrens Hospital of Shanghai
Shanghai, China
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Ege Üniversitesi Hastanesi Pediatrik Gastroenteroloji Bölümü
Bornova, İzmir, 35100, Turkey (Türkiye)
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Guangzhou Women And Childrens Medical Center
Guangzhou, China
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Hacettepe Universitesi ihsan Dogramaci Cocuk Hastansesi
Ankara, 06230, Turkey (Türkiye)
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Hadassah Medical Center
Jerusalem, Israel
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Hospital Raja Perempuan Azinab II
Kota Bharu, Kelantan, 15586, Malaysia
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KK Women's and Children's Hospital
Singapore, Singapore
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Linkou Chang Gung Memorial Hospital
Taoyuan, Taiwan
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National Chen Kung University Hospital
Tainan, Taiwan
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National Taiwan University Hospital
Taipei, Taiwan
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Queen Mary Hospital
Hong Kong, Hong Kong
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Queensland Childrens Hospital
South Brisbane, Queensland, 4101, Australia
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Royal Childrens Hospital
Parkville, Victoria, 3104, Australia
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Shaare-Zedek Medical Center
Jerusalem, Israel
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Starship Child Health
Auckland, 1142, New Zealand
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Stollery Children's Hospital
Edmonton, Alberta, Canada
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Taichung Veterans General Hospital
Taichung, Taiwan
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University Malaya Medical Center
Kuala Lumpur, 59100, Malaysia
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Women's and Children's Hospital
North Adelaide, South Australia, 5006, Australia