New MRI scans could unlock ALS mysteries and speed up drug discovery

NCT ID NCT03362658

Ongoing Knowledge-focused Sponsor: University of Alberta Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether advanced MRI techniques can measure brain changes in people with ALS (Lou Gehrig's disease). Researchers will scan 119 participants three times over 8 months to see if these scans can track the disease and help diagnose it earlier. The goal is to create better tools for testing new treatments, which could lead to faster discovery of therapies for ALS.

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Conditions

The condition(s) this trial relates to.

amyotrophic lateral sclerosis motor neuron disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AMYOTROPHIC LATERAL SCLEROSIS MOTOR NEURON DISEASE

Contacts and locations

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Locations

Laval University

Québec, Quebec, G1V 0A6, Canada
McGill University / Montreal Neurological Institute and Hospital

Montreal, Quebec, H3A 2B4, Canada
University of Alberta

Edmonton, Alberta, T6G 2B7, Canada
University of Calgary / Heritage Medical Research Clinic

Calgary, Alberta, T2N 4Z6, Canada
University of Miami

Miami, Florida, United States
University of Toronto / Sunnybrook Health Sciences Centre

Toronto, Ontario, M4N 3M5, Canada
University of Utah

Salt Lake City, Utah, 84108, United States

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