Spinal cord cell transplant aims to slow ALS

NCT ID NCT02478450

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This trial investigates whether injecting Q-Cells—specialized human cells that support nerve function—into the spinal cord is safe for people with ALS. Up to 30 participants receive injections in the lower or upper spinal cord, with some receiving higher doses. Researchers monitor side effects and measure changes in muscle strength, breathing, and daily function to see if the treatment might slow the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Q-Cells (human glial restricted progenitor cells)
What this could lead to
If safe and effective, this cell therapy could slow or stabilize ALS progression by replacing damaged support cells in the spinal cord.
What could go wrong
This is an early-phase trial with only 30 participants, so results may not apply broadly. Risks include side effects from the injection procedure or the cells themselves.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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