Could a simple scan replace invasive heart tests for millions with chest pain?

NCT ID NCT06070662

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study is testing whether advanced CT and MRI scans can diagnose coronary microvascular disease (CMD) without needing an invasive angiogram. CMD affects the heart's tiny blood vessels and causes chest pain in many people with no major artery blockages. Researchers will compare the new scans against standard invasive tests in 20 patients to see if they can accurately spot the condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to a non-invasive way to diagnose coronary microvascular disease, replacing the need for invasive angiograms and reducing patient discomfort and risk.
What could go wrong
This is a very small pilot study with only 20 participants, so results may not apply to everyone. The new imaging techniques may not be accurate enough to replace current invasive tests.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Glenfield Hospital, University Hospitals of Leicester

    RECRUITING

    Leicester, Leicestershire, United Kingdom

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Other studies related to the condition(s) this trial covers.