Could a simple blood or urine test replace prostate biopsies?

NCT ID NCT06144619

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether non-invasive tests—like blood, urine, and genetic analysis—can help track prostate cancer progression without repeated biopsies. Researchers will follow 500 men with low, intermediate, or high-risk prostate cancer as they receive standard care. The goal is to find biomarkers that signal when the disease is getting worse, potentially reducing the need for invasive procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to better ways to monitor prostate cancer without repeated invasive biopsies, improving patient comfort and care decisions.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly improve health. It is currently suspended, and results may not change practice for years.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

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