New combo therapy shows promise for lung cancer brain metastases

NCT ID NCT02696993

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study is for people with advanced non-small cell lung cancer that has spread to the brain. It tests whether adding immunotherapy drugs (nivolumab with or without ipilimumab) to radiation therapy can better control the cancer. The goal is to find the safest and most effective dose and to see if it helps stop the brain tumors from growing. Participants will receive either stereotactic radiosurgery or whole brain radiation along with the immunotherapy.

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Conditions

The condition(s) this trial relates to.

brain cancer metastatic malignant neoplasm in the brain non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States