New combo therapy aims to control hard-to-treat colorectal and pancreatic cancers

NCT ID NCT03104439

First seen Jan 12, 2026 · Last updated May 14, 2026 · Updated 21 times

Summary

This study tests whether combining two immunotherapy drugs (nivolumab and ipilimumab) with radiation therapy can help control colorectal and pancreatic cancers that are either microsatellite stable (MSS) or MSI-high. About 84 adults with these cancers will receive the treatment. The main goal is to see how many patients achieve disease control (tumor shrinkage or stability).

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Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

Conditions

Explore the condition pages connected to this study.