Heart surgery gas study pulled before it began

NCT ID NCT03748082

Terminated Knowledge-focused Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study was designed to test whether giving nitric oxide gas during heart surgery could help protect blood vessels in patients with pre-existing vessel problems. It was an add-on to a larger trial and planned to enroll adults having elective heart surgery with prolonged bypass. However, the study was withdrawn before any participants were enrolled, so no results are available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Nitric Oxide

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder Hemolysis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIOVASCULAR DISEASES CARDIOVASCULAR RISK FACTOR ENDOTHELIAL DYSFUNCTION HEMOLYSIS INTRAVASCULAR

Contacts and locations

Locations

Boston Medical Center

Boston, Massachusetts, 02118, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States

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