Laser light to the brain may lift depression

NCT ID NCT05435820

Completed Symptom relief Sponsor: Peruvian Clinical Research Source: ClinicalTrials.gov ↗

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study tests whether shining a specific type of near-infrared light on the front of the brain can safely help people with major depressive disorder. The light is thought to boost energy production in brain cells, which may improve mood. Researchers will measure changes in depression scores over six weeks in 50 adults.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: near-infrared transcranial laser therapy
What this could lead to: If it works, this could offer a non-invasive, drug-free option to ease depression symptoms.
What could go wrong: This is an early study with only 50 participants, so results may not apply broadly. The treatment may not improve depression or could cause side effects.

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Conditions

The condition(s) this trial relates to.

depressive disorder major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSION DISORDERS MAJOR DEPRESSIVE DISORDER

Contacts and locations

Locations

Clinica Vesalio

Lima, Lima Province, 15037, Peru
Hospital Nacional Guillermo Almenara Irigoyen

Lima, Lima Province, 15034, Peru
Hospital Nacional Hipolito Unanue

Lima, Lima Province, 15007, Peru

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