Can cutting nicotine in vapes reduce addiction?
NCT ID NCT05205382
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looked at how different nicotine levels in e-cigarettes affect addiction and chemical exposure in young users aged 21-35. Researchers tested pods with 5%, 3%, and 0% nicotine in 116 participants. The goal was to see if reducing nicotine could make vaping less addictive, which could help guide future regulations.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
nicotine (at 5%, 3%, and 0% concentrations in e-cigarette pods)
What this could lead to
If successful, this research could inform policies that make e-cigarettes less addictive for young people.
What could go wrong
This is a completed observational study, not a treatment trial. Results may not directly change products or behavior outside the lab.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Florida International University
Miami, Florida, 33199, United States