Can cutting nicotine in vapes reduce addiction?

NCT ID NCT05205382

First seen Jun 26, 2026 · Last updated Aug 14, 2026 · Updated 2 times

Summary

This study looked at how different nicotine levels in e-cigarettes affect addiction and chemical exposure in young users aged 21-35. Researchers tested pods with 5%, 3%, and 0% nicotine in 116 participants. The goal was to see if reducing nicotine could make vaping less addictive, which could help guide future regulations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
nicotine (at 5%, 3%, and 0% concentrations in e-cigarette pods)
What this could lead to
If successful, this research could inform policies that make e-cigarettes less addictive for young people.
What could go wrong
This is a completed observational study, not a treatment trial. Results may not directly change products or behavior outside the lab.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Vaping

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Florida International University

    Miami, Florida, 33199, United States

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