New balloon aims to reduce heart rhythm problems during valve replacement

NCT ID NCT06816485

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new balloon device used during a minimally invasive heart valve replacement procedure (TAVI) for people with severe aortic stenosis. The main goal is to see if the balloon causes fewer heart rhythm problems, like blockages that might need a pacemaker. About 93 participants will be followed for up to 7 days after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

PTV Balloon (a balloon device used to open the heart valve before and after placing a new valve)

What this could lead to

If successful, this could lead to a safer way to perform TAVI, reducing the risk of heart rhythm problems that require a pacemaker.

What could go wrong

This is an early-stage, small study (93 people) with very short follow-up (7 days). The device may not reduce risks as hoped, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

aortic disorder aortic valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital Clínico Universitario de Valladolid (HCUV)

    RECRUITING

    Valladolid, 47003, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitari de Bellvitge

    RECRUITING

    Barcelona, 08907, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitario 12 de Octubre

    RECRUITING

    Madrid, 28041, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitario Juan Ramon Jimenez

    RECRUITING

    Huelva, 21005, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitario Ramon y Cajal

    RECRUITING

    Madrid, 28034, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitario Reina Sofia

    RECRUITING

    Córdoba, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitario Virgen del Rocio

    RECRUITING

    Seville, 41013, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitario y Politécnico La Fe

    RECRUITING

    Valencia, 46026, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital de la Santa Creu i Sant Pau

    RECRUITING

    Barcelona, 08025, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••