AORTIC DISEASES

This study follows 1,200 people who received special fabric tubes (grafts) to repair or replace damaged arteries in the neck, belly, or legs. Researchers want to see how well the grafts work over time and how often problems like blockages or infections happen. It is an observatio…

This study tests a new balloon device used during a minimally invasive heart valve replacement procedure (TAVI) for people with severe aortic stenosis. The main goal is to see if the balloon causes fewer heart rhythm problems, like blockages that might need a pacemaker. About 93 …

This study tests a special balloon that uses shockwaves to crack calcium buildup in the iliac arteries, making it possible to deliver large aortic stents. About 40 adults with severe aortic disease and hardened arteries will be enrolled. The goal is to see if this approach is saf…

This study tests a new device called Rapidlink, used during open surgery to repair or replace blood vessels in the chest. It involves 150 adults already scheduled for aortic surgery. The goal is to see if the device reduces major complications like stroke or death. Participants w…

This study tests a new device called the Encompass F2, which is designed to catch debris that might travel to the brain during a common heart valve replacement procedure (TAVR). The goal is to see if it reduces the risk of stroke and brain damage compared to standard care. About …

This study compares two methods of pain control for people having open abdominal surgery. One group gets a single injection of a long-lasting numbing medicine into the belly muscles during surgery. The other group gets a standard numbing medicine through small tubes placed in the…

This study is creating a large database of information from 10,000 adults undergoing heart surgery. Researchers will collect detailed data before, during, and after surgery to identify factors that affect recovery and complications. The goal is to improve risk prediction, persona…

This study tracks 300 adults with aortic disease to measure how their condition impacts quality of life, fatigue, mental health, and ability to work. Researchers will use questionnaires over 12 months to gather data. The goal is to better understand these challenges and help desi…

This study will use a new type of cardiac MRI to look at the heart's microscopic structure in 1,000 people—both healthy volunteers and those with various heart conditions. The goal is to see if this advanced imaging can detect early signs of heart damage better than standard test…

This study is gathering 5,000 people with certain gene changes that raise the risk of aortic disease (like aneurysms or dissections). Researchers will track their health over time to see how these genes affect the condition. The goal is to better predict and manage the disease, n…