First-of-its-Kind cancer drug targets 'Guardian Gene' mutation
NCT ID NCT06778863
Summary
This is a first-in-human study testing a new drug called CLSP-1025 for adults with advanced solid tumors that have a specific genetic change called the p53 R175H mutation. The main goals are to find a safe dose and see if the drug can help control the cancer. The drug works by engaging the patient's own immune system to attack cancer cells that carry this specific mutation.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Baylor University Medical Center
RECRUITINGDallas, Texas, 75246, United States
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Duke Cancer Institute
RECRUITINGDurham, North Carolina, 27701, United States
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Fox Chase Cancer Center
RECRUITINGPhiladelphia, Pennsylvania, 19111, United States
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Fred Hutchinson Cancer Center
RECRUITINGSeattle, Washington, 98109, United States
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Hackensack University Medical Center
RECRUITINGHackensack, New Jersey, 07601, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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HonorHealth Research Institute
RECRUITINGScottsdale, Arizona, 85258, United States
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Johns Hopkins - Sidney Kimmel Comprehensive Cancer Center
RECRUITINGBaltimore, Maryland, 21287, United States
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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Mary Crowley Cancer Research
RECRUITINGDallas, Texas, 75230, United States
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
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NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
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Sarah Cannon Research Institute (SCRI) Oncology Partners
RECRUITINGNashville, Tennessee, 37203, United States
Contact Phone: •••-•••-••••
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The University of Arizona Cancer Center
RECRUITINGTucson, Arizona, 85719, United States
Contact Email: •••••@•••••
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The University of Chicago Comprehensive Cancer Center
RECRUITINGChicago, Illinois, 60637, United States
Contact Phone: •••-•••-••••
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Thomas Jefferson University, Sidney Kimmel Cancer Center
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
Contact Email: •••••@•••••
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USC - Norris Comprehensive Cancer Center
RECRUITINGLos Angeles, California, 90033, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California Davis Comprehensive Cancer Center
RECRUITINGSacramento, California, 95817, United States
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University of California San Francisco
RECRUITINGSan Francisco, California, 94143, United States
Contact Email: •••••@•••••
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University of Kentucky Markey Cancer Center
RECRUITINGLexington, Kentucky, 40536, United States
Contact Phone: •••-•••-••••
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University of Miami - Sylvester Comprehensive Cancer Center
RECRUITINGMiami, Florida, 33136, United States
Contact Phone: •••-•••-••••
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Vanderbilt University Medical Center
RECRUITINGNashville, Tennessee, 37232, United States
Contact Phone: •••-•••-••••
Conditions
Explore the condition pages connected to this study.