Ear device zaps nerves to tame stubborn high blood pressure?
NCT ID NCT05179343
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tested a device that sends mild electrical pulses to a nerve in the ear, aiming to lower blood pressure in people whose hypertension is not controlled by medication. 63 adults took part, and the device was compared to a sham (fake) version. The goal was to see if the treatment is safe, acceptable, and effective at reducing daytime blood pressure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
AffeX-CT device (trans-cutaneous vagal nerve stimulation)
What this could lead to
If it works, this could offer a new non-drug option to help control high blood pressure.
What could go wrong
This is a small pilot study, so results may not apply to everyone. The device may not lower blood pressure enough to be useful, and long-term effects are unknown.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Barts Health NHS Trust
London, E1 1FR, United Kingdom