Alcohol injection around prostate may stall cancer spread

NCT ID NCT07100847

Ongoing Disease control Sponsor: University of Texas Southwestern Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 17, 2026 · Updated 3 times

Summary

This early-stage study tests whether injecting alcohol around the prostate can block nerve signals that may help cancer grow and spread. Twenty-one men with high-risk prostate cancer who plan to have their prostate removed will receive one or two injections before surgery. Researchers will check if the treatment reduces nerve activity in the prostate and slows cancer progression.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dehydrated alcohol (ethanol) injected around the prostate
What this could lead to: If it works, this could point toward a way to slow or stop the spread of high-risk prostate cancer by blocking nerve signals.
What could go wrong: This is a very early Phase 1 trial with only 21 people, so it is not yet proven to work. The nerve block may not slow cancer growth and could affect sexual or urinary function.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NERVES NEUROBIOLOGY OF CANCER NEUROLYSIS PROSTATE CANCER

Contacts and locations

Locations

University of Texas Southwestern Medical Center

Dallas, Texas, 75390, United States

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