Nerve block may reduce Post-Surgery pain in breast cancer patients

NCT ID NCT04327063

Completed Symptom relief Sponsor: Institut Curie Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether a nerve block using ropivacaine could reduce pain after breast cancer surgery compared to a placebo. 182 women having breast-conserving surgery with sentinel lymph node biopsy took part. The goal was to see if fewer patients needed strong painkillers in the first three hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ropivacaine
What this could lead to: If it works, this could offer a better way to manage pain after breast cancer surgery, reducing the need for strong painkillers.
What could go wrong: This is a completed Phase 3 trial, but results may not apply to all patients or surgeries. The nerve block may not provide significant benefit over placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma in situ breast neoplasm invasive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MALIGNANT NEOPLASM OF BREAST

Contacts and locations

Locations

Centre Jean Perrin

Clermont-Ferrand, 63000, France
Hopital Tenon

Paris, 75020, France
Institut Curie

Paris, 75005, France
Institut de Cancérologie de Lorraine

Vandœuvre-lès-Nancy, 54500, France

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