Glue injection could seal pancreas after cancer surgery

NCT ID NCT07230509

First seen Nov 17, 2025 · Last updated Jun 19, 2026 · Updated 25 times

Summary

This study tests whether injecting a medical glue (N-butyl-2-cyanoacrylate) into the pancreas during surgery can prevent dangerous leaks. About 90 patients with pancreatic or nearby cancers will receive either standard surgery or surgery plus the glue injection. The goal is to see if the glue makes the connection between the pancreas and intestine stronger and reduces complications.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Liver and GIT hospital , Minia University

    RECRUITING

    Minya, Minya Governorate, 61519, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

N-butyl-2-cyanoacrylate (a medical glue) mixed with Lipiodol

What this could lead to

If it works, this could reduce the risk of a serious pancreatic leak after surgery, making recovery safer and shorter for patients.

What could go wrong

This is an early phase 2 trial with only 90 participants. The glue might cause allergic reactions or not work as expected. Results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

Anastomotic Leak malignant pancreatic neoplasm pancreatic neoplasm periampullary adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.