Glue injection could seal pancreas after cancer surgery

NCT ID NCT07230509

Recruiting now Disease control Sponsor: Minia University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether injecting a medical glue (N-butyl-2-cyanoacrylate) into the pancreas during surgery can prevent dangerous leaks. About 90 patients with pancreatic or nearby cancers will receive either standard surgery or surgery plus the glue injection. The goal is to see if the glue makes the connection between the pancreas and intestine stronger and reduces complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: N-butyl-2-cyanoacrylate (a medical glue) mixed with Lipiodol
What this could lead to: If it works, this could reduce the risk of a serious pancreatic leak after surgery, making recovery safer and shorter for patients.
What could go wrong: This is an early phase 2 trial with only 90 participants. The glue might cause allergic reactions or not work as expected. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Anastomotic Leak malignant pancreatic neoplasm pancreatic neoplasm periampullary adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PANCREAS CANCER PANCREATICODUODENECTOMY PERIAMPULLARY CANCER POSTOPERATIVE PANCREATIC FISTULA

Contacts and locations

Locations

Liver and GIT hospital , Minia University
RECRUITING

Minya, Minya Governorate, 61519, Egypt

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