Can a Plant-Based supplement ease long COVID? new trial aims to find out

NCT ID NCT07397910

Not yet recruiting Symptom relief Sponsor: Universidad Católica San Antonio de Murcia Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether a natural supplement (made from orange, grapefruit, olive leaf, and other plant extracts) combined with a personalized exercise program can help people with long COVID. The trial will include 40 adults who still have symptoms like inflammation and fatigue at least 3 months after their COVID-19 infection. Researchers will measure changes in inflammation markers and symptom severity over 4 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: a dietary supplement containing orange extract, apigenin, luteolin, yerba mate extract, grapefruit extract, and olive leaf extract
What this could lead to: If it works, this could point toward a safe, natural way to reduce long COVID symptoms and improve quality of life.
What could go wrong: This is a very small early trial with only 40 people, so results may not apply to everyone. The supplement is a mix of natural compounds, and its effects are not proven yet.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

long COVID-19 Motor Activity post-COVID-19 disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LONG COVID

Contacts and locations

Locations

UCAM HiTech, Sport & Health Innovation Hub

Murcia, Spain

More trials for these conditions

Other studies related to the condition(s) this trial covers.