Nasal spray could ease stent pain after kidney stone surgery

NCT ID NCT06158620

Recruiting now Symptom relief Sponsor: University of Texas Southwestern Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares a nasal spray form of ketorolac (Sprix) to oral diclofenac pills for managing pain from ureteral stents placed after kidney stone surgery. Researchers will enroll 80 adults to see if the nasal spray provides faster pain relief and reduces unplanned doctor visits. The goal is to improve comfort and quality of life for patients with these stents.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: intra-nasal ketorolac (Sprix) and oral diclofenac
What this could lead to: If the nasal spray works better, it could offer faster pain relief and fewer emergency visits for people with ureteral stents after kidney stone surgery.
What could go wrong: This is an early-phase trial with only 80 people, so results may not apply to everyone. The nasal spray might not be more effective than the standard pill, and side effects are possible.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative ureterolithiasis urolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POST-OPERATIVE PAIN STENT COMPLICATION URETER CALCULI UROLITHIASIS

Contacts and locations

Locations

UT Southwestern Medical Center
RECRUITING

Dallas, Texas, 75390, United States

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