Can a gentle nasal breeze keep lungs safe after surgery?

NCT ID NCT01887015

Completed Prevention Sponsor: University Hospital, Clermont-Ferrand Source: ClinicalTrials.gov ↗

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This trial asks whether giving patients a steady stream of warm, moist oxygen through a nasal tube right after abdominal surgery can prevent low blood oxygen levels, a common and serious complication. It enrolls adults at intermediate to high risk of lung problems who are having abdominal surgery lasting at least two hours. Half receive the nasal high-flow oxygen, and half receive standard oxygen therapy, with the goal of seeing which approach better keeps oxygen levels in a safe range.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Nasal high flow oxygen therapy delivered through a heated, humidified cannula
What this could lead to: If effective, this simple breathing support could become a standard way to prevent dangerous drops in blood oxygen after abdominal surgery, reducing complications and speeding recovery.
What could go wrong: This is a mid-stage trial, and results may not apply to all patients. The therapy may not reduce hypoxemia enough to matter, and some people may find the nasal cannula uncomfortable.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSTOPERATIVE HYPOXEMIA

Contacts and locations

Locations

CHU Clermont-Ferrand

Clermont-Ferrand, 63003, France

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