Sleep disorder drugs may impact heart and mind – new study investigates

NCT ID NCT05371483

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Mayo Clinic study will follow 100 adults with narcolepsy or idiopathic hypersomnia who are starting a new treatment. Researchers will measure changes in blood pressure over 24 hours and track eye movements during a simple mental test before and after at least 3 months on medication. The goal is to understand how common treatments affect both the heart and the brain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors choose safer treatments for narcolepsy and idiopathic hypersomnia by understanding their effects on blood pressure and thinking skills.
What could go wrong: This is an observational study, not a treatment trial. It will not test whether a drug works, only measure changes. Results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

idiopathic hypersomnia narcolepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IDIOPATHIC HYPERSOMNIA NARCOLEPSY

Contacts and locations

Locations

Mayo Clinic Arizona

Scottsdale, Arizona, 85259, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.