New alert aims to curb opioid overdoses by nudging doctors to Co-Prescribe naloxone
NCT ID NCT06271668
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a computer alert that reminds doctors to prescribe naloxone—a drug that reverses opioid overdoses—alongside high-risk opioid prescriptions. The alert appears when a doctor orders an opioid for patients aged 12-89 (excluding those with cancer or hospice care). Researchers will compare how often naloxone is co-prescribed with and without the alert, and track overdose rates over six months. The goal is to make it easier for doctors to follow best practices and save lives.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
naloxone
What this could lead to
If successful, this alert could increase naloxone prescribing and help prevent opioid overdoses.
What could go wrong
The alert may not change doctor behavior, or patients may not fill the naloxone prescription. The study is observational, so it cannot prove cause and effect.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Colorado Hospital
Aurora, Colorado, 80045, United States