Can an app save lives from overdose? philly trial aims to find out

NCT ID NCT06466005

Recruiting now Disease control Sponsor: Drexel University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 21, 2026 · Updated 2 times

Summary

This study tests whether a smartphone app called UnityPhilly can help bystanders quickly respond to opioid overdoses with naloxone. About 450 adults who live or work in three Philadelphia neighborhoods will use the app and receive training. Researchers will track how many overdoses are signaled through the app and how many are successfully reversed over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: UnityPhilly app (smartphone app for coordinating overdose response)
What this could lead to: If successful, this app could help save lives by getting naloxone to overdose victims faster, reducing deaths in high-risk areas.
What could go wrong: This is a single-city study with 450 participants, so results may not apply elsewhere. App usage and response rates may be lower than expected, limiting real-world impact.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Opiate Overdose acute opioid poisoning prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OPIOID OVERDOSE

Contacts and locations

Locations

Drexel University
RECRUITING

Philadelphia, Pennsylvania, 19104, United States

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