New naloxone spray tested for faster overdose help

NCT ID NCT05377255

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new device (AP003) that delivers naloxone as a nasal spray to reverse opioid overdoses. Twenty-four healthy adults received multiple doses to see how the drug moves through the body and to check for side effects. The goal was to compare the new spray with an existing one (Narcan) and ensure it is safe and effective.

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Conditions

The condition(s) this trial relates to.

acute opioid poisoning Opiate Overdose

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Syneos Health Clinical Research Services

    Miami, Florida, 33136, United States

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