ER opioid overdose study pulled before it began

NCT ID NCT03968237

Terminated Disease control Sponsor: Nassima Ait-Daoud Tiouririne Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study aimed to help people who had an opioid overdose by starting them on buprenorphine/naloxone in the emergency room and then connecting them to an addiction clinic. The goal was to reduce repeat overdoses and improve treatment engagement. However, the study was withdrawn before enrolling any participants, so no data was collected.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: buprenorphine/naloxone
What this could lead to: If successful, this approach could help people recover from opioid overdose by starting medication in the ER and connecting them to ongoing addiction care.
What could go wrong: The study was withdrawn before enrolling anyone, so no results are available. It was a small pilot, and even if tested, success in linking patients to treatment is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute opioid poisoning opiate dependence Opiate Overdose

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OPIOID OVERDOSE

Contacts and locations

Locations

UVA Center for Leading Edge Addiction Research

Charlottesville, Virginia, 22903, United States

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