Can a simple pill prevent pancreatitis after ERCP? new study tests two drugs
NCT ID NCT06252441
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether taking oral N-Acetyl cysteine before an ERCP procedure could prevent pancreatitis as well as the standard treatment, rectal diclofenac. Forty-six adults at risk for pancreatitis after ERCP received one of the two drugs. The goal was to see which drug better reduces inflammation and prevents pancreatitis from developing.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
N-Acetyl cysteine and diclofenac
What this could lead to
If it works, this could point toward a safer or more effective way to prevent pancreatitis after ERCP.
What could go wrong
This is a small, early-phase study with only 46 participants, so results may not apply to everyone. The drugs may not work as hoped or could cause side effects.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Obstructive Jaundice Clinic in the National Liver Institute, Menoufia University , Shebin Elkoom
Menofia, Egypt