Can a simple pill prevent pancreatitis after ERCP? new study tests two drugs
NCT ID NCT06252441
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether taking oral N-Acetyl cysteine before an ERCP procedure could prevent pancreatitis as well as the standard treatment, rectal diclofenac. Forty-six adults at risk for pancreatitis after ERCP received one of the two drugs. The goal was to see which drug better reduces inflammation and prevents pancreatitis from developing.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- N-Acetyl cysteine and diclofenac
- What this could lead to
- If it works, this could point toward a safer or more effective way to prevent pancreatitis after ERCP.
- What could go wrong
- This is a small, early-phase study with only 46 participants, so results may not apply to everyone. The drugs may not work as hoped or could cause side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Obstructive Jaundice Clinic in the National Liver Institute, Menoufia University , Shebin Elkoom
Menofia, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a simple ice water flush prevent pancreatitis after a common procedure?
- Common painkiller may prevent pancreatitis after bile duct procedure
- When to remove pancreatic stents? new trial aims to find out
- Can a double dose stop Post-Procedure pancreatitis?
- Could a Half-Dose of a common drug prevent a painful complication just as well?