Could extra stool tests catch bowel cancer earlier and save colonoscopies?

NCT ID NCT07430540

Not yet recruiting Diagnosis Sponsor: University of Edinburgh Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to improve early detection of bowel cancer by having patients provide multiple stool samples (FIT tests) instead of just one. About 1,000 people referred to a hospital in Scotland with possible bowel cancer symptoms will take part. The goal is to see if tracking changes in blood levels over time can better identify who needs a colonoscopy, reducing unnecessary procedures and catching cancers earlier.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: FIT (faecal immunochemical test) stool test
What this could lead to: If successful, this could lead to a more accurate and efficient way to detect bowel cancer early, reducing the need for unnecessary colonoscopies and saving healthcare resources.
What could go wrong: This is an early implementation study with 1000 participants, not a large-scale trial. The new pathway may not improve detection rates as hoped, and there is a small risk of missed cancers.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL CANCER SIGNIFICANT BOWEL PATHOLOGY

Contacts and locations

Locations

NHS Lothian

Edinburgh, United Kingdom

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