Can therapy and exercise boost knee replacement results?

NCT ID NCT03771430

Completed Symptom relief Sponsor: Lovisenberg Diakonale Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 12, 2026 · Updated 3 times

Summary

This study looks at whether adding cognitive behavioral therapy (CBT) and exercise to knee replacement surgery helps reduce pain and improve function. About 282 adults with knee osteoarthritis are randomly assigned to one of three groups: a non-surgical program with CBT and exercise, surgery followed by CBT and exercise, or surgery with standard care. The main goal is to measure changes in knee pain using a patient questionnaire.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cognitive behavioral therapy and exercise
What this could lead to: If successful, this could show that combining therapy and exercise with surgery reduces pain and improves recovery for knee osteoarthritis patients.
What could go wrong: This is a mid-sized trial, and the benefits may not apply to all patients. The added therapy may not significantly improve outcomes over standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DEGENERATIVE JOINT DISEASE OF KNEE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEGENERATIVE JOINT DISEASE OF KNEE OSTEOARTHRITIS; PRIMARY

Contacts and locations

Locations

Haukeland University Hospital - Kysthospitalet Hagevik

Bergen, Norway
Lovisenberg Diaconal Hospital

Oslo, Norway
Martina Hansens Hospital

Oslo, Norway, Norway

More trials for these conditions

Other studies related to the condition(s) this trial covers.