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Can foot and pelvis moves ease stubborn knee pain?

NCT ID NCT07806929

Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

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Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
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Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
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First seen Sep 08, 2026 · Last updated Sep 09, 2026 · Updated 1 time

Summary

This trial tests whether adding Mulligan mobilization, a type of hands-on therapy applied to the foot or the pelvis, to a standard hip-knee exercise program can reduce pain and improve function in people with patellofemoral pain and flat feet. Researchers will compare three groups over four weeks: one doing exercises alone, one adding foot mobilization, and one adding pelvis mobilization. Participants are adults aged 18 to 35 with knee pain lasting at least six weeks and signs of foot pronation. The main outcomes are pain intensity and knee function, with secondary measures including muscle strength and joint alignment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Mulligan mobilization of the foot or ilium (pelvis) added to a hip-knee exercise program
What this could lead to
If adding these hands-on techniques works, it could point to a more effective physical therapy approach for patellofemoral pain, reducing pain and improving knee function without surgery.
What could go wrong
This is a small, short-term trial, so results may not apply widely. The added benefit of mobilization over exercises alone remains uncertain, and some people may not respond to manual therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age of the subjects between 18-35 years 2. BMI was from 18.5 to ≤ 29.5 Kg/m² . 3. Anterior or retro patellar knee pain for at least 6 weeks duration. 4. Foot posture index score from +6 to + 12. 5. Sagittal plane innominate tilt angle more than 8 degrees. 6. Pain elicited at least by two of the following four screening tests; (i) isometric muscle contraction with slight bent knee,(ii) palpation of the patella, (iii) patellar compression against the femoral bone (iv) active resisted knee extension. 7. Pain provoked by at least two of the following activities: running, walking, hopping, squatting, stair negotiation, kneeling, or prolonged sitting Exclusion Criteria: 1. Meniscal or other intra-articular pathologic conditions; cruciate or collateral ligament involvement. 2. A history of traumatic patellar subluxation or dislocation.. 3. Previous surgery in the knee, ankle and hip joints. 4. Knee, ankle and hip joints osteoarthritis. 5. Taking non-steroidal anti-inflammatory drugs or corticosteroids within 24 hours before the test. 6. History of brain injury or vestibular disorder within the last 6 months. 7. Pregnant female.

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Conditions

The condition(s) this trial relates to.

flatfoot patellofemoral pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Flatfeet Patellofemoral pain, PFP

How to take part

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  1. The places running it

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  2. The official record

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Contacts and locations

Locations

  • Al-Zaytoonah University of Jordan

    Amman, 11733, Jordan

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