New MRI scan could spot liver cancer earlier in High-Risk patients

NCT ID NCT06658782

Recruiting now Diagnosis Sponsor: University of Oxford Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether a 20-minute MRI scan without dye can detect liver cancer earlier than the usual ultrasound in 300 people with cirrhosis who are at high risk. Participants will get both scans every 6 months for 30 months. The goal is to see if the MRI catches cancers that ultrasound might miss, while being safer and cheaper than contrast scans.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: non-contrast magnetic resonance imaging (MRI) scan
What this could lead to: If successful, this could offer a safer, more accurate way to spot liver cancer early in people with cirrhosis, potentially saving more lives.
What could go wrong: This is a feasibility study with only 300 participants. The MRI may not prove better than ultrasound in practice, and results may not apply to all groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver Fibrosis hepatitis C induced liver cirrhosis hepatocellular carcinoma prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CIRRHOSIS CIRRHOSIS AND CHRONIC LIVER DISEASE CIRRHOSIS DUE TO HEPATITIS B CIRRHOSIS DUE TO HEPATITIS C CIRRHOSIS OF THE LIVER HEPATOCELLULAR CARCINOMA

Contacts and locations

Locations

Bournemouth University Hospital
RECRUITING

Bournemouth, United Kingdom
Oxford University Hospitals NHS Foundation Trudt
RECRUITING

Oxford, Oxon, ox3 9du, United Kingdom

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