New MRI technique may help personalize treatment for childhood eye cancer

NCT ID NCT03267459

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a special type of MRI scan can predict how children with retinoblastoma, a rare eye cancer, will respond to chemotherapy delivered directly to the eye. Researchers will scan 60 children before treatment and check if the scan results match their response 18 months later. The goal is to find early signs that could guide treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

dynamic contrast-enhanced MRI

What this could lead to

If successful, this could help doctors identify early which children will benefit from intra-arterial chemotherapy, allowing for more personalized treatment plans.

What could go wrong

This is an early-stage observational study with only 60 participants, so results may not apply to all children. The MRI technique may not reliably predict outcomes in practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

retinoblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fondation A De Rothschild

    RECRUITING

    Paris, 75019, France

    Contact Email: •••••@•••••