New MRI scan could reveal hidden acidity in prostate tumors

NCT ID NCT05851365

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests a new MRI technique that uses a special form of bicarbonate to measure how acidic prostate tumors are. Ten men with localized prostate cancer will receive an injection of hyperpolarized bicarbonate before an MRI scan. The goal is to see if this method is safe and can produce clear images of tissue acidity, which may help doctors better understand and treat prostate cancer in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Hyperpolarized bicarbonate (13C)

What this could lead to

If successful, this imaging method could help doctors measure acidity in prostate tumors without a biopsy, potentially guiding treatment decisions.

What could go wrong

This is a very early pilot study with only 10 participants. It is testing feasibility and safety, not treatment effectiveness. The technique may not work as hoped or may not be practical for wider use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California, San Francisco

    San Francisco, California, 94143, United States