Precision radiation boost aims to improve prostate cancer treatment

NCT ID NCT05364229

Ongoing Disease control Sponsor: University Health Network, Toronto Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether using MRI guidance to deliver an extra dose of radiation directly to the tumor can improve prostate cancer treatment. Forty men with localized prostate cancer will receive standard radiation to the whole prostate plus a targeted boost to the visible tumor. Researchers will check if this approach is feasible and safe, and will follow participants for up to 5 years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Radiation therapy (MR-guided radiotherapy boost)
What this could lead to: If successful, this approach could improve tumor control and reduce side effects for men with localized prostate cancer.
What could go wrong: This is a small, early feasibility study with only 40 participants. It is not designed to prove effectiveness, and results may not apply to all prostate cancer patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CANCER

Contacts and locations

Locations

University Health Network, Princess Margaret Hospital

Toronto, Ontario, M5G 2M9, Canada

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