Can MRI replace unnecessary biopsies for prostate cancer patients?

NCT ID NCT04692675

First seen Jun 25, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study looks at whether a special MRI scan (mpMRI) can better monitor prostate cancer in men who choose active surveillance instead of immediate treatment. About 500 men with low-risk prostate cancer will get regular MRIs, biopsies, and blood tests over several years. The goal is to see if MRI can accurately detect cancer growth and possibly reduce the need for repeat biopsies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

multiparametric magnetic resonance imaging (mpMRI)

What this could lead to

If successful, this could show that mpMRI helps doctors better track prostate cancer progression, potentially reducing the need for frequent biopsies.

What could go wrong

This is an observational study, not a treatment trial. It may not change current practice, and results depend on how well imaging matches biopsy findings.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Disease Progression prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-••••