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Can a website ease the emotional toll of stem cell transplants?

NCT ID NCT06960993

Symptom relief Sponsor: Northwestern University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 08, 2026 · Last updated Aug 04, 2026 · Updated 3 times

Summary

This trial tests whether a specially designed website, called Mosaic, can help blood cancer patients who are about to undergo a stem cell transplant feel less distressed and have a better quality of life. Participants are randomly assigned to use either the Mosaic website or a standard educational website. They complete surveys before their transplant and again at 2, 4, 6, and 8 months after to measure changes in psychological distress, physical symptoms, and overall well-being.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Mosaic intervention website
What this could lead to
If it works, this could provide a simple, scalable way to support emotional and physical well-being for stem cell transplant patients.
What could go wrong
This is a behavioral intervention, not a drug, so benefits may be modest. The trial is relatively small and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 356 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2025

Expected to finish

Feb 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosed with a hematologic cancer according to medical records * Scheduled for or preparing for scheduling of an allogeneic or autologous stem cell transplant at one of our study sites * Aged 18 or older (no upper limit) * English or Spanish Proficient * Interested in using a website to learn about stem cell transplant * Ability to understand and willingness to sign an informed consent document and comply with all study procedures Exclusion Criteria: * Currently participating in a behavioral intervention targeting distress, health-related quality of life, or symptoms * Undergoing the first in a planned tandem stem cell transplant * Unable to provide meaningful consent (severe cognitive impairment or language difficulties)

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Conditions

The condition(s) this trial relates to.

hematopoietic and lymphoid cell neoplasm hematopoietic and lymphoid system neoplasm leukemia lymphoma myelodysplastic syndrome Myelodysplastic Syndromes plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bone marrow transplant Hematologic malignancy Leukemia Lymphoma Multiple myeloma Myelodysplastic syndromes Stem cell transplant

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    3 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Georgetown University School of Medicine

    RECRUITING

    Washington D.C., District of Columbia, 20057, United States

  • Hackensack Meridian Health

    RECRUITING

    Nutley, New Jersey, 07110, United States

  • Northwestern University Feinberg School of Medicine

    RECRUITING

    Chicago, Illinois, 60611, United States

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