New combo attack shows promise against tough pancreatic tumors

NCT ID NCT03991962

First seen Nov 10, 2025 · Last updated Jun 18, 2026 · Updated 42 times

Summary

This study tests a two-step treatment for people with pancreatic cancer that hasn't spread but can't be removed by surgery. First, patients receive a stronger chemotherapy cocktail (modified FOLFIRINOX), followed by precise, high-dose radiation (SBRT). The goal is to see if this approach delays cancer growth better than older treatments. The trial enrolled 28 adults with borderline or locally advanced pancreatic cancer.

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Contacts and locations

Locations

  • Yale University School of Medicine

    New Haven, Connecticut, 06511, United States

Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm pancreatic adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.