POTS brain fog targeted in new drug study

NCT ID NCT01988883

First seen Jan 16, 2026 · Last updated Jun 08, 2026 · Updated 17 times

Summary

This early-phase study tests whether a single dose of modafinil, a drug that promotes wakefulness, can improve concentration and mental clarity in people with Postural Tachycardia Syndrome (POTS). About 20 adults diagnosed with POTS will take the drug and then complete computer-based tests of attention and thinking. The goal is to better understand the 'brain fog' common in POTS and explore potential treatment options.

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Contacts and locations

Locations

  • Vanderbilt University

    Nashville, Tennessee, 37211, United States

Conditions

Explore the condition pages connected to this study.