New supplement aims to rebuild knee cartilage – early trial underway
NCT ID NCT07323745
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether Mobithron Advance, a daily oral supplement made from undenatured type II collagen, can slow or reverse cartilage loss in people with knee osteoarthritis. Over 12 months, 84 participants will take either the supplement or a placebo. Researchers will use MRI scans to measure cartilage thickness and track pain scores, aiming to see if the drug can modify the disease rather than just ease symptoms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
undenatured type II collagen (UC-II) oral tablets
What this could lead to
If it works, this could point toward a treatment that slows or reverses cartilage loss in knee osteoarthritis, potentially reducing pain and delaying the need for surgery.
What could go wrong
This is a very early (Phase 1) trial with only 84 people, so results may not be conclusive. The supplement may not work better than placebo, and long-term safety is still being studied.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hospital Univerisiti Sains Malaysia (HUSM)
RECRUITINGKota Bharu, Kelantan, 16150, Malaysia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-••••
Contact