Can a smartphone app help tame chronic pain and opioid cravings?
NCT ID NCT05152134
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a digital program called 'Empowered Relief: On-Demand' to see if it could help people with chronic pain who misuse prescription opioids. 234 adults with chronic pain and opioid misuse were randomly assigned to either the digital pain relief program or a health education program. Researchers measured pain intensity, opioid craving, and misuse over three months to see if the digital program improved outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Empowered Relief On-Demand (digital behavioral intervention)
- What this could lead to
- If it works, this could offer a convenient, online way to help people with chronic pain reduce their pain and cut back on opioid misuse.
- What could go wrong
- This is a completed Phase 3 trial, but it's relatively small (234 participants) and relies on self-reported outcomes. The digital intervention may not work for everyone, and results may not apply to all populations.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Stanford University
Palo Alto, California, 94304, United States
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