Artificial liver device tested in humans for first time
NCT ID NCT06285253
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage trial tested a device called miroliverELAP, which uses a bioengineered liver graft to filter blood outside the body, in 10 adults with acute liver failure. The goal was to check safety and see if it can support the liver for up to 48 hours, giving time for recovery or a transplant. Results are not yet available, but the study is complete.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bioengineered liver graft (miroliverELAP)
What this could lead to
If successful, this device could provide temporary liver support for patients with acute liver failure, giving the liver time to heal or bridging to a transplant.
What could go wrong
This is a very early phase 1 trial with only 10 participants, focused on safety. The device may not work as hoped, and there are risks of serious side effects from the blood-circulation procedure.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Cleveland Clinic Foundation
Cleveland, Ohio, 44195, United States
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Intermountain Healthcare
Salt Lake City, Utah, 84103, United States
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Mayo Clinic
Rochester, Minnesota, 55902, United States
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Mount Sinai Recanati/Miller Transplantation Institute
New York, New York, 10029, United States
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Northwestern Memorial Hospital
Chicago, Illinois, 60611, United States
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University of Michigan Medical School
Ann Arbor, Michigan, 48109, United States
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University of Minnesota Medical School
Minneapolis, Minnesota, 55455, United States
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Virginia Commonwealth University Medical Center
Richmond, Virginia, 23970, United States