Can a short CBT session curb Post-Surgery opioid dependence?
NCT ID NCT07783672
First seen Aug 25, 2026 · Last updated Aug 26, 2026 · Updated 1 time
Summary
This trial tests whether adding a brief, skills-based cognitive behavioral therapy (CBT) session to standard transitional pain care helps people recovering from surgery. Participants are adults with chronic pain or a history of substance use who take daily opioids. The study compares those receiving mini-CBT plus transitional pain care against those receiving transitional pain care alone, looking at hospital readmissions, opioid use, and chronic post-surgical pain.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- A brief, skills-based mini-cognitive behavioral therapy (CBT) group intervention added to standard transitional pain service care
- What this could lead to
- If it works, adding mini-CBT to transitional pain care could reduce long-term opioid use and chronic pain after surgery.
- What could go wrong
- This is an early-stage trial, and the added benefit of mini-CBT over standard care alone may be small or uncertain. Results may not apply to all surgical patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 400 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Feb 2027
An estimate. Start dates often move.
- Expected to finish
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May 2031
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Chronic pain syndrome Patients with a h/o or current substance use Patients on a daily opioid dose (morphine equivalency) of ≥90 Consulted for transitional pain service Exclusion Criteria: Not seen by transitional pain service
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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UT MD Anderson Cancer Center
Houston, Texas, 77030, United States
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