Nerve zapping: which side works best for migraines?

NCT ID NCT06894121

Completed Symptom relief Sponsor: Ankara City Hospital Bilkent Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether treating the greater occipital nerve on one side or both sides of the head with pulsed radiofrequency provides better migraine relief. 217 adults with episodic or chronic migraine who did not respond well to preventive medications received the procedure under ultrasound guidance. The main goal was to see how many headache days per month changed over 6 months, along with pain intensity and disability scores.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: pulsed radiofrequency treatment of the greater occipital nerve
What this could lead to: If successful, this could show which nerve treatment approach (one side or both sides) works better for reducing migraine days and pain.
What could go wrong: This is a completed study, but results are not yet published. The treatment is a procedure, not a drug, and may not work for everyone. Risks include pain, infection, or nerve damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEADACHE DISORDERS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

headache disorder migraine disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEADACHE DISORDERS MIGRAINE, GREATER OCCIPITAL NERVE PULSED RADIOFREQUENCY ULTRASOUND GUIDED NERVE BLOCK

Contacts and locations

Locations

Health Sciences University, Ankara Bilkent City Hospital

Ankara, Cankaya, 06800, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.