Blood biomarkers may flag epilepsy patients at risk of sudden death

NCT ID NCT03419000

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at whether tiny molecules in the blood, called microRNAs, can identify epilepsy patients who have dangerous drops in oxygen during seizures. Researchers compared 50 drug-resistant epilepsy patients undergoing video-EEG monitoring, splitting them into those who had breathing problems during seizures and those who did not. The goal is to find a simple blood test that could predict risk of sudden unexpected death in epilepsy (SUDEP).

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a blood test that identifies epilepsy patients at higher risk of sudden unexpected death (SUDEP), enabling closer monitoring or preventive strategies.

What could go wrong

This is a small, early-stage observational study (75 participants) looking at biomarkers, not a treatment trial. The findings may not translate into a reliable clinical test or reduce SUDEP risk.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

disease Drug Resistant Epilepsy focal epilepsy generalized epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospices Civils de Lyon

    Bron, 69500, France

  • Service de Neurophysiologie Clinique Hôpital La Timone

    Marseille, 13005, France