Blood biomarkers may flag epilepsy patients at risk of sudden death
NCT ID NCT03419000
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looked at whether tiny molecules in the blood, called microRNAs, can identify epilepsy patients who have dangerous drops in oxygen during seizures. Researchers compared 50 drug-resistant epilepsy patients undergoing video-EEG monitoring, splitting them into those who had breathing problems during seizures and those who did not. The goal is to find a simple blood test that could predict risk of sudden unexpected death in epilepsy (SUDEP).
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a blood test that identifies epilepsy patients at higher risk of sudden unexpected death (SUDEP), enabling closer monitoring or preventive strategies.
- What could go wrong
- This is a small, early-stage observational study (75 participants) looking at biomarkers, not a treatment trial. The findings may not translate into a reliable clinical test or reduce SUDEP risk.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hospices Civils de Lyon
Bron, 69500, France
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Service de Neurophysiologie Clinique Hôpital La Timone
Marseille, 13005, France
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