Could a gut bacteria transplant save lungs from sepsis?
NCT ID NCT07342205
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether transplanting healthy gut bacteria (fecal microbiota) can help people with acute lung injury caused by sepsis. Sepsis triggers severe inflammation that often damages the lungs, and current treatments are limited. The trial will compare standard care plus a placebo against standard care plus the bacteria transplant in 60 adults. Researchers will measure oxygen levels, survival at 28 days, and ICU stay length.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
human-derived active intestinal bacterial liquid (fecal microbiota transplant)
What this could lead to
If it works, this could offer a new treatment to reduce deaths and improve recovery in sepsis patients with lung injury.
What could go wrong
This is an early phase 2/3 trial with only 60 people. The treatment may not work better than placebo, and risks like infection or gut issues are possible.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Putuo Hospital, Shanghai University of Traditional Chinese Medicine
RECRUITINGShanghai, Putuo, 421000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••